Moderna's COVID-19 Vaccine Shines In Clinical Trial
Nov 23, 2020 15:53:56 GMT -8
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GaliWalker likes this
Post by High Sierra Fan on Nov 23, 2020 15:53:56 GMT -8
Your immune system is a normal part of your body and you develop new antibodies against intruder proteins every day of your life. All a vaccine does is present some specific protein structures for your immune system to react to as it’s doing every day anyway; no possibility of any years out side effects.
A vaccine is an introduction or two of a specific protein, then your human immunological system does its completely routine job.
These vaccines aren’t “drugs” that might have interactions at low but significant over time levels with body processes other than the intended target in either a subset of patients or a majority due to slight structural similarities of the binding sites.
“Auto immune”? Were our bodies to have exposed protein structures similar to the coronavirus horn protein structure? The vaccine wouldn’t work, our anti-self regulatory immune system process would simply ignore the familiar protein introduced by the vaccine and there’d be no disease protection. From the trials the vaccines do generate an immune response: so the introduced proteins have no structural similarities to any in our bodies. Meaning no “autoimmune” activity is possible. Our immune systems are specifically evolved/designed to avoid that. There are failures, the disease that effects the ion channel family central to my research, myasthenia graves, is one of those, but we’re very strongly set up to NOT have that happen.
Frankly the mRNA and dna based vaccines look safer than traditional ones to the extent I’ve seen little mention of adjuvant (immune system stimulator traditionally used to boost an immune reaction to the tiny amount of introduced foreign protein), possibly because as the genetic approach generates much more target foreign protein than a vaccine injection and so eliminates the need for a stimulus. Adjuvants, being chemicals that are biologically active can induce at least short term side effects, inflammation or joint pain at times. But with only one or two injections, the adjuvant goes away and the side reaction fades.
A vaccine is an introduction or two of a specific protein, then your human immunological system does its completely routine job.
These vaccines aren’t “drugs” that might have interactions at low but significant over time levels with body processes other than the intended target in either a subset of patients or a majority due to slight structural similarities of the binding sites.
“Auto immune”? Were our bodies to have exposed protein structures similar to the coronavirus horn protein structure? The vaccine wouldn’t work, our anti-self regulatory immune system process would simply ignore the familiar protein introduced by the vaccine and there’d be no disease protection. From the trials the vaccines do generate an immune response: so the introduced proteins have no structural similarities to any in our bodies. Meaning no “autoimmune” activity is possible. Our immune systems are specifically evolved/designed to avoid that. There are failures, the disease that effects the ion channel family central to my research, myasthenia graves, is one of those, but we’re very strongly set up to NOT have that happen.
Frankly the mRNA and dna based vaccines look safer than traditional ones to the extent I’ve seen little mention of adjuvant (immune system stimulator traditionally used to boost an immune reaction to the tiny amount of introduced foreign protein), possibly because as the genetic approach generates much more target foreign protein than a vaccine injection and so eliminates the need for a stimulus. Adjuvants, being chemicals that are biologically active can induce at least short term side effects, inflammation or joint pain at times. But with only one or two injections, the adjuvant goes away and the side reaction fades.
